PMID

Data

Article Title

Organization

Design, synthesis and structure-activity relationships of novel phenylalanine-based amino acids as kainate receptors ligands.

Jagiellonian University Medical College

Synthesis of willardiine and 6-azawillardiine analogs: pharmacological characterization on cloned homomeric human AMPA and kainate receptor subtypes.

University of Bristol

4-Alkylidenyl glutamic acids, potent and selective GluR5 agonists.

Eli Lilly

(S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid, a potent and selective agonist at the GluR5 subtype of ionotropic glutamate receptors. Synthesis, modeling, and molecular pharmacology.

The Danish University of Pharmaceutical Sciences

Pyrrolylquinoxalinediones carrying a piperazine residue represent highly potent and selective ligands to the homomeric kainate receptor GluR5.

Abbott

4-Alkyl- and 4-cinnamylglutamic acid analogues are potent GluR5 kainate receptor agonists.

Eli Lilly

Pharmacological characterization of the competitive GLUK5 receptor antagonist decahydroisoquinoline LY466195 in vitro and in vivo.

Eli Lilly